Pentanoic acid, 2-chloro-3-methyl-, (2S,3S)-

Pentanoic acid, 2-chloro-3-methyl-, (2S,3S)- - Names and Identifiers

Name	(2S,3S)-2-CHLORO-3-METHYL-N-VALERIC ACID
Synonyms	(2S,3S)-2-CHLORO-3-METHYLVALERIC ACID (2S,3S)-2-Chloro-3-methylvaleric Acid (2S,3S)-2-CHLORO-3-METHYL-N-VALERIC ACID Pentanoic acid, 2-chloro-3-methyl-, (2S,3S)-
CAS	32653-34-2

Pentanoic acid, 2-chloro-3-methyl-, (2S,3S)- - Physico-chemical Properties

Molecular Formula	C6H11ClO2
Molar Mass	150.6
Density	1.12
Boling Point	125 °C / 15mmHg
pKa	3.04±0.29(Predicted)
Storage Condition	Room Temprature
Refractive Index	-4.5 ° (C=neat)
MDL	MFCD00191403

Pentanoic acid, 2-chloro-3-methyl-, (2S,3S)- - Introduction

(2S,3S)-2-chloro-3-methyll-n-valeric ACID is an organic compound with the chemical formula C7H13ClO2. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: Colorless to light yellow liquid
-Molecular weight: 160.63g/mol
-Melting point: About -44 ℃
-Boiling point: About 197 ℃

Use:
- (2S,3S)-2-choro-3-methyl-n-valeric ACID is widely used in the field of drug synthesis and can be used as intermediates for synthetic drugs, pesticides, bioactive molecules, etc.
-It can also be used as a catalyst for acylation and Ketonization reactions for organic synthesis.

Method:
The preparation of (2S,3S)-2-choro-3-methyl-n-valeric ACID can be carried out by the following steps:
1. Under appropriate reaction conditions, 2-methyl pentanoic acid was reacted with cuprous chloride to obtain 2-methyl Glutaric acid chloride.
2. 2-methylglutaric ACID chloride is reacted with an enantioselective reducing agent in the presence of sodium carbonate to obtain (2S,3S)-2-chloroo-3-methyl-n-valeric ACID.

Safety Information:
- (2S,3S)-2-chroo-3-methyl-n-valeric ACID irritant to eyes and skin. Personal protective equipment should be worn during operation to avoid direct contact.
-During storage and transportation, it should be avoided from contact with strong oxidants, strong acids and strong bases to prevent dangerous reactions.
-If inhalation or skin contact occurs, immediately move to a well-ventilated place and rinse the affected area with plenty of water.
-If ingestion occurs, seek medical attention immediately and show the safety data sheet or product label.

Last Update：2024-04-09 02:00:51